Session Talk

The landscape of alternative polyadenylation in CD8 T cells in single-cell transcriptome

Lixinyu Liu, Jiayu Wen
Alternative cleavage and polyadenylation (APA) ena...

#single cell #deep learning #machine learning #immunology #transcriptomics

Session Talk

RNase III-CLASH of multi-drug resistant Staphylococcus aureus reveals a regulatory mRNA 3’UTR required for intermediate vancomycin resistance

Daniel G. Mediati, Julia L. Wong, Wei Gao, Stuart MacKellar, Chi Nam Ignatius Pang, Sylvania Wu, Winton Wu, Brandon Sy, Ian Monk, Joanna Richmond, Benjamin Howden, Tim P. Stinear, Sander Granneman, Jai J. Tree
Treatment of methicillin-resistant Staphylococcus ...

#transcriptomics #networks #resistance #bacteria

PhosR enables processing and functional analysis of phosphoproteomic data

Jieun Kim, Taiyun Kim, Nolan J Hoffman, Di Xiao, David James, Sean J Humphrey, Pengyi Yang
Mass spectrometry (MS)-based phosphoproteomics has...

#proteomics #gene function #gene regulation

Integrated transcriptional and chromatin accessibility profiling uncovers sex-specific adipose tissue imprinting of regulatory T cells

David Chisanga, Ajith Vasanthakumar, Wei Shi, Axel Kallies
Integrated transcriptional and chromatin accessibi...

#transcriptomics #chromatin #sex differences

Session Talk

Integrated transcription factor profiling with transcriptome analysis: identification of L1PA2 transposons as global regulatory modulators in a breast cancer model

Jiayue-Clara Jiang, Joe Rothnagel, Kyle Upton
LINE1 retrotransposons occupy approximately 17% of...

#transcriptomics #cancer #disease #transposable elements

Invited Keynote

Features of functional human genes

Paul Gardner, Helena Cooper
Proteins and non-coding RNAs are functional produc...

#genomics #transcriptomics #gene function #non-coding RNA #evolution

Detection and identification of cis-regulatory elements using change-point and classification algorithms

Dominic Maderazo, Jennifer Flegg, Manjula Algama, Mirana Ramialison, Jonathan Keith
Transcriptional regulation is primarily mediated b...

#sequence analysis #sequence alignment #classification algorithms

Session Talk

A predictive model for commonly-repressed polycomb-target genes dissects DNA sequence from gene expression

Emma Gail, Sonika Tyagi, Chen Davidovich
BACKGROUND: Histone H3 lysine 27 trimethylation (H...

#machine learning #epigenetics #transcription #gene regulation #gene expression

A Deep Learning Approach to Recover Combination of Biologically Significant Motifs

Tarun Bonu, Sonika Tyagi
DNA or RNA motifs are short (5-20 bp) recurring pa...

#deep learning #machine learning #sequence analysis #gene regulation

3DFAACTS-SNP: Using regulatory T cell-specific epigenomics data to uncover candidate mechanisms of Type-1 Diabetes (T1D) risk

Ning Liu, Timothy Sadlon, Ying Ying Wong, Stephen Pederson, Simon Barry, Jimmy Breen
Background
Genome-wide association studies (GW...

#Hi-C #transcription #GWAS #gene function