linc2function: Predicting function of lncRNA transcripts using an Artificial Neural Network (ANN) Model Yashpal Ramakrishnaiah, Levin Kuhlmann, Sonika TyagiLong Noncoding RNAs (LncRNA) modulate cellular pro... #deep learning #transcriptomics #non-coding RNA #gene function
Using equivalence classes for differential transcript usage and variant detection in RNA-seq data Marek Cmero, Breon Schmidt, Ian Majewski, Paul Ekert, Nadia Davidson, Alicia OshlackRNA sequencing (RNA-seq) has enabled high-throughp... #transcriptomics #cancer #alternative splicing #disease
Session Talk RNA splicing is a hierarchical supernetwork that co-operates to drive osteoblast differentiation Angel LiangSplicing is essential for the proper expression of... #development #transcriptomics #clustering #gene regulation #proteomics
Quick determination of RNA-Seq strandedness with how_are_we_stranded_here Beth Signal, Tim KahlkeRNA-Seq is a commonly performed method to analyse ... #transcriptomics #methods #benchmarking
Session Talk Moving beyond RNA sequence: uncovering the functional role of RNA structure Vincent Corbin, Phillip Tomezko, Paromita Gupta, Margalit Glasgow, Sitara Persad, Lachlan McIntosh, Anthony Papenfuss, Silvia RouskinRNA is unique among biomolecules in its possession... #gene regulation #RNA splicing #viruses #RNA structure
Session Talk Implementing an integrated analysis to identify and validate circular RNAs using patient-derived neuronal stem cells. Oak Hatzimanolis, Alan Mackay-Sim, Alexandre CristinoIn recent years it has been determined that a larg... #transcriptomics #circular RNAs #disease
Session Talk Features that determine 5’ cryptic splice site selection in genetic disorders Ruebena Dawes, Sandra CooperBackground:Splicing variants are a common cau... #RNA splicing #biomedical informatics #disease #sequence variation
Direct RNA sequencing identifies isoform specific structures Yue WanThe ability to correctly assign structure informat... #RNA structure #long reads #alternative splicing #RNA function
Comprehensive analysis of usability and archival stability of RNA-seq tools Karishma Chhugani, Dhrithi Deshpande, Serghei MangulAs technology has advanced, RNA-seq methods have b... #transcriptomics #reproducibility #open source #methods
Characterisation of transcript expression in placenta across early gestation reveals variable transcript usage Konstantinos Bogias, Stephen Pederson, Qianhui Wan, Melanie Smith, James Breen, Claire RobertsThe human placenta is a rapidly developing, highly... #transcriptomics #alternative splicing #development #pregnancy #RNA splicing
Session Talk Application of mixture model to RNA-seq data to discover ageing regulators Sasdekumar Loganathan, Atefeh Taherian Fard, Jessica Mar, Ameya KulkarniAgeing is a complex process where the combined eff... #transcriptomics #statistics #ageing
An integrated approach for interrogating the dynamics of co-transcriptional splicing with unparalleled depth and minimal bias A.J. Sethi, Rippei HayashiAlthough dysregulated alternative splicing underli... #RNA splicing #gene regulation #splicing dynamics
A machine learning model to predict splice factor expression directly from transcriptome-wide splicing patterns A.J. Sethi, Pablo Acera Mateos, Renzo Balboa, Emiliana Weiss, Attila HorvathDysregulated splicing is a major driver of cancer ... #RNA splicing #networks #gene regulation #machine learning
