genozip: an advanced universal compressor for genomic data files

Divon Lan0
(0) University of Adelaide

Find me on Wed Nov 25th, 1:30-2:50pm AEDT in Remo, table 44

Abstract
genozip is a new universal lossless compressor for genomic data files. It supports all common genomic data formats, such as FASTQ, SAM/BAM, VCF, FASTA. genozip is designed as a drop-in replacement for gzip for data archival and transfer. It compresses 3 to 5 times better than gzip, and significantly faster. genozip provides significant gains in time and cost related to CPU usage and data storage and transfer.

genozip also offers some advanced features: data are encrypted with AES-256 to ensure security and privacy (with –password), MD5 is calculated on-the-fly (with –md5), and multiple files can be bound into a single genozip file for efficient delivery and storage. While lossless by default, genozip also offers the –optimize option, which modifies the data in ways that are usually harmless for downstream analysis, but significantly improve the compression.

genozip is open source and available on github, conda and DockerHub.